PEBC: Theme of the Week: Stringent Storage Requirements

We have all counselled patients to put certain medications in the fridge to preserve its stability, including vaccines and reconstituted suspensions. Rarely, there are certain items which have an unusual storage requirement - either strictly room temperature or in its original packaging.


Here are some unusual ones you may not know of:


1) Room temperature suspensions: Reconstituted suspensions such as Biaxin (clarithromycin) or Dalacin (clindamycin) should be kept at room temperature because these liquids become thick and hard to pour once chilled.


2) Pradaxa (dabigatran): these anticoagulant capsules should be kept in its original container because it is sensitive to moisture, and may lose its efficacy if exposed, putting patients at risk for clots.


3) Mestinon (pyridostigmine): these tablets for myasthenia gravis are sensitive to moisture - hence should be kept in its original bottle. Exposure to moisture results in a change from white to brown colour (mottled appearance), which is harmless.


4) Aggrenox (dipyridamole/acetylsalicylic acid) and Constella (linaclotide): original containers are recommended.





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