PEBC: Theme of the Week: Using a Medication for a Different Route [Part 2]

Continuing from Part 1 where we looked at liquid formulations, let's have a look at some more unusual off-label routes of administration.

---------

1) Prometrium (progesterone) capsules: originally used orally to treat menopause and menstrual cycle irregularities, these capsules may be inserted vaginally to bypass systemic metabolism and its adverse effects, or to support a pregnancy locally.

---------

2) Flovent (fluticasone) metered dose inhaler: this corticosteroid spray is usually inhaled for asthma, but a prescriber may use it as an off-label spray to the skin to reduce irritation and redness.

---------

3) Mupirocin ointment: usually to treat topical infections, this ointment may also be used to treat Staphylococus in the sinuses. Some specialists recommend squeezing mupirocin into a nasal irrigation bottle with saline solution. After shaking and dissolving the mupirocin, the contents can be squeezed into the nostrils as a sinus rinse.

---------

4) Metronidazole tablets: an oral antibiotic to treat anaerobes, some doctors recommend crushing metronidazole tablets and applying it directly to wounds as a form of treatment for distressing odours.

---------

Have you seen any other unusual prescribing of medications with a different route of administration? Let us know in the comments!





12 views0 comments